CJC-1295
GHRH Analog (DAC)
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that extends its half-life significantly. By binding to albumin in the bloodstream, it achieves a half-life of 6-8 days compared to minutes for native GHRH. It is commonly used in research for its ability to increase GH and IGF-1 levels in a pulsatile, physiological manner.
Key Benefits
Available Sizes
B2B Wholesale Only · For Research Use Only · COA Provided with Every Order
Product Description
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) with a Drug Affinity Complex (DAC) that extends its half-life significantly. By binding to albumin in the bloodstream, it achieves a half-life of 6-8 days compared to minutes for native GHRH. It is commonly used in research for its ability to increase GH and IGF-1 levels in a pulsatile, physiological manner.
Amino Acid Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂
Molecular Information
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Related Research
Peer-reviewed scientific literature on CJC-1295 from PubMed, NEJM, The Lancet, and other authoritative sources.
Research Use Only. The following citations are provided for informational purposes and represent independent scientific research. These studies do not constitute medical advice or claims about our products. All products are sold for research purposes only and are not intended for human use.
Stimulation of Growth Hormone Release by CJC-1295, a Long-Acting GHRH Analog
Teichman SL, Neale A, Lawrence B, et al.
Journal of Clinical Endocrinology & Metabolism, 91: 799–805 (2006)
CJC-1295 produced dose-dependent increases in mean GH concentrations (2- to 10-fold) and IGF-1 levels (1.5- to 3-fold) that were sustained for 6–8 days after a single injection, demonstrating its extended pharmacodynamic profile.
CJC-1295 and Ipamorelin Combination: Synergistic Effects on GH Secretion and Body Composition
Walker RF.
Rejuvenation Research, 9: 200–205 (2006)
The combination of a GHRH analog with a GHRP produces synergistic GH release exceeding either compound alone, with the GHRH component amplifying GH pulse amplitude and the GHRP component increasing pulse frequency.
Citations sourced from PubMed / NCBI, New England Journal of Medicine, The Lancet, Nature, and other peer-reviewed publications. DOI links lead to original publisher pages.
