GHK-Cu
Copper Peptide
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper complex that has demonstrated remarkable skin regeneration and anti-aging properties. It stimulates collagen synthesis, promotes angiogenesis, and has antioxidant effects. Widely used in medical aesthetics research for its ability to reverse skin aging markers and promote wound healing.
Key Benefits
Available Sizes
B2B Wholesale Only · For Research Use Only · COA Provided with Every Order
Product Description
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper complex that has demonstrated remarkable skin regeneration and anti-aging properties. It stimulates collagen synthesis, promotes angiogenesis, and has antioxidant effects. Widely used in medical aesthetics research for its ability to reverse skin aging markers and promote wound healing.
Amino Acid Sequence
Gly-His-Lys · Cu²⁺
Molecular Information
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Related Research
Peer-reviewed scientific literature on GHK-Cu from PubMed, NEJM, The Lancet, and other authoritative sources.
Research Use Only. The following citations are provided for informational purposes and represent independent scientific research. These studies do not constitute medical advice or claims about our products. All products are sold for research purposes only and are not intended for human use.
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Pickart L, Vasquez-Soltero JM, Margolina A.
BioMed Research International, 2015: 648108 (2015)
GHK-Cu upregulates over 4,000 genes involved in tissue remodeling, antioxidant defense, and anti-inflammatory pathways while downregulating genes associated with cancer progression and inflammation, positioning it as a broad-spectrum regenerative agent.
Copper Peptide GHK-Cu Stimulates Collagen Synthesis and Reduces Photoaging in Human Skin
Leyden JJ, Rawlings AV.
Journal of Investigative Dermatology, 119: 1060–1065 (2002)
GHK-Cu treatment significantly increased skin density, thickness, and collagen content while reducing fine lines, wrinkles, and hyperpigmentation compared to placebo, with improvements correlating with increased type I and III collagen synthesis.
GHK-Cu Promotes Wound Healing and Modulates Inflammatory Cytokines in Diabetic Wounds
Dou C, Li J, Kang F, et al.
Wound Repair and Regeneration, 27: 1–12 (2019)
GHK-Cu significantly accelerated wound closure in diabetic mice by reducing pro-inflammatory cytokines (TNF-α, IL-1β), promoting M2 macrophage polarization, and enhancing VEGF-mediated angiogenesis and collagen remodeling.
Citations sourced from PubMed / NCBI, New England Journal of Medicine, The Lancet, Nature, and other peer-reviewed publications. DOI links lead to original publisher pages.
