NAD+
Nicotinamide Adenine Dinucleotide
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells and is essential for cellular energy metabolism. It plays a critical role in DNA repair, sirtuin activation, and mitochondrial function. NAD+ levels decline with age, making supplementation a key focus in longevity and anti-aging research. Our pharmaceutical-grade NAD+ is suitable for IV and subcutaneous research applications.
Key Benefits
Available Sizes
B2B Wholesale Only · For Research Use Only · COA Provided with Every Order
Product Description
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells and is essential for cellular energy metabolism. It plays a critical role in DNA repair, sirtuin activation, and mitochondrial function. NAD+ levels decline with age, making supplementation a key focus in longevity and anti-aging research. Our pharmaceutical-grade NAD+ is suitable for IV and subcutaneous research applications.
Amino Acid Sequence
N/A (Coenzyme, not a peptide sequence)
Molecular Information
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Related Research
Peer-reviewed scientific literature on NAD+ from PubMed, NEJM, The Lancet, and other authoritative sources.
Research Use Only. The following citations are provided for informational purposes and represent independent scientific research. These studies do not constitute medical advice or claims about our products. All products are sold for research purposes only and are not intended for human use.
NAD+ Metabolism and Its Roles in Cellular Processes During Ageing
Covarrubias AJ, Perrone R, Grozio A, Verdin E.
Nature Reviews Molecular Cell Biology, 22: 119–141 (2021)
NAD+ levels decline significantly with age in multiple tissues, and this decline is causally linked to hallmarks of aging including mitochondrial dysfunction, genomic instability, and impaired stem cell function. NAD+ supplementation reverses several age-related physiological declines in preclinical models.
Nicotinamide Riboside and NAD+ Precursors Improve Mitochondrial Function in Aged Mice
Yoshino J, Mills KF, Yoon MJ, Imai SI.
Cell Metabolism, 14: 528–536 (2011)
NAD+ precursor supplementation restored NAD+ levels in aged mice to those of young animals, significantly improving mitochondrial function, energy metabolism, insulin sensitivity, and physical activity—effectively reversing several metabolic aspects of aging.
Safety and Metabolism of Long-term Administration of NAD+ Precursors in Healthy Adults
Martens CR, Denman BA, Mazzo MR, et al.
Nature Communications, 9: 1286 (2018)
NR supplementation was safe and well-tolerated, significantly increasing NAD+ levels in whole blood by 60% compared to placebo, with favorable effects on blood pressure and aortic stiffness in participants with elevated baseline values.
Citations sourced from PubMed / NCBI, New England Journal of Medicine, The Lancet, Nature, and other peer-reviewed publications. DOI links lead to original publisher pages.
