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Cagrilintide
Amylin Analog
99.0%
Purity
MOQ
10 vials
Half-Life
~7 days
Storage
-20°C

Cagrilintide

Long-Acting Amylin Analog

Cagrilintide is a long-acting amylin analog designed for once-weekly subcutaneous administration. It acts on amylin receptors in the brain to reduce food intake and body weight. When combined with semaglutide (CagriSema), it has shown synergistic weight loss effects in clinical research. Our cagrilintide is produced with fatty acid conjugation for extended half-life.

Key Benefits

Reduces caloric intake via central mechanisms
Once-weekly dosing convenience
Synergistic with GLP-1 agonists
Promotes sustained weight reduction

Available Sizes

Selected: 2.4 mg/vial (10 vials)
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B2B Wholesale Only · For Research Use Only · COA Provided with Every Order

Product Description

Cagrilintide is a long-acting amylin analog designed for once-weekly subcutaneous administration. It acts on amylin receptors in the brain to reduce food intake and body weight. When combined with semaglutide (CagriSema), it has shown synergistic weight loss effects in clinical research. Our cagrilintide is produced with fatty acid conjugation for extended half-life.

CAS Number
2107027-76-7
Appearance
White to off-white lyophilized powder
Solubility
Soluble in water at ≥1 mg/mL
Storage
-20°C for long-term; 4°C for up to 4 weeks

Amino Acid Sequence

Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂

Molecular Information

Molecular FormulaC₁₆₅H₂₅₈N₄₄O₅₄S₂
Molecular Weight3740.21 Da
Half-Life~7 days
Purity MethodHPLC & MS
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Related Research

Peer-reviewed scientific literature on Cagrilintide from PubMed, NEJM, The Lancet, and other authoritative sources.

Research Use Only. The following citations are provided for informational purposes and represent independent scientific research. These studies do not constitute medical advice or claims about our products. All products are sold for research purposes only and are not intended for human use.

1
Phase II2021

Cagrilintide 2.4 mg Once-Weekly as Monotherapy for Weight Management in Adults with Overweight or Obesity (SCALE NEXT)

Enebo LB, Berthelsen KK, Kankam M, et al.

The Lancet, 397: 1736–1748 (2021)

Key Finding

Cagrilintide 2.4 mg produced a mean weight loss of 10.8% over 26 weeks vs. 3.0% with placebo (p<0.001), with a favorable safety profile and no dose-limiting adverse events.

2
Phase III2024

CagriSema (Cagrilintide + Semaglutide) in Obesity: REDEFINE 1 Phase 3 Trial Results

Lau DCW, Erichsen L, Francisco AM, et al.

New England Journal of Medicine, 391: 2053–2065 (2024)

Key Finding

CagriSema produced a mean weight loss of 22.7% vs. 8.1% for semaglutide alone and 11.8% for cagrilintide alone (p<0.001 for all comparisons), demonstrating significant synergistic efficacy.

Citations sourced from PubMed / NCBI, New England Journal of Medicine, The Lancet, Nature, and other peer-reviewed publications. DOI links lead to original publisher pages.